CAS: | 88-73-3 | Product Name: | 2-Nitrochlorobenzene |
---|---|---|---|
Appearance: | Fused Crystalline Mass | MF: | C6H4ClNO2 |
Density: | 1.348 G/mL At 25 °C(lit.) | Melting Point: | 31-33 °C(lit.) |
Boiling Point: | 246 °C(lit.) | EINECS: | 201-854-9 |
High Light: | 88-73-3 2 Nitrochlorobenzene,CAS 88-73-3,C6H4ClNO2 2 Nitrochlorobenzene |
88-73-3 2-Nitrochlorobenzene C6H4ClNO2 Fused Crystalline Mass
Nitrochlorobenzene is typically synthesized by nitration of chlorobenzene in the presence of sulfuric acid:
C6H5Cl + HNO3 → O2NC6H4Cl + H2O
This reaction affords a mixture of isomers. Using an acid ratio of 30/56/14, the product mix is typically 34-36% 2-nitrochlorobenzene and 63-65% 4-nitrochlorobenzene, with only about 1% 3-nitrochlorobenzene.
Alkylation and electrophilic aromatic substitution can occur at the chlorinated carbon center, and a diverse array of reactions can be carried out using the nitro group. 2-Nitrochlorobenzene can be reduced to the 2-chloroaniline with Fe/HCl mixture, the Bechamp reduction. Treatment of 2-nitrochlorobenzene with sodium methoxide gives 2-nitroanisole.
Specification
Product Name: | 2-Nitrochlorobenzene |
Synonyms: | 1-CHLORO-2-NITROBENZENE;2-cnb;2-CHLORONITROBENZENE;2-Chloro-1-nitrobenzene;2-NITROCHLOROBENZENE;chloro-1nitro-2benzene;Chloro-o-nitrobenzene;Nitrochlorobenzene, o- |
CAS: | 88-73-3 |
MF: | C6H4ClNO2 |
MW: | 157.55 |
EINECS: | 201-854-9 |
Product Categories: | alkyl chloride| nitro-compound;Building Blocks;Chemical Synthesis;Nitro Compounds;Nitrogen Compounds;Organic Building Blocks;Alpha Sort;Analytical Standards;AromaticsVolatiles/ Semivolatiles;C;CAlphabetic;CHChemical Class;Chemical Class;ChloroAnalytical Standards;Halogenated;Nitro Compounds;Nitrogen Compounds;Organic Building Blocks;Agrochemical Intermediates;Benzene derivatives;Intermediates of Dyes and Pigments |
Mol File: |
88-73-3.mol |
Melting point | 31-33 °C(lit.) |
Boiling point | 246 °C(lit.) |
density | 1.348 g/mL at 25 °C(lit.) |
vapor density | 5.4 (vs air) |
vapor pressure | 0.04 mm Hg ( 25 °C) |
refractive index | 1.5520 (estimate) |
Fp | >230 °F |
storage temp. | Store below +30°C. |
solubility | alcohol: soluble |
form | Fused Crystalline Mass |
color | Yellow |
PH | 6 (0.4g/l, H2O, 20℃) |
explosive limit | 1.15-13.1%(V) |
Water Solubility | 0.43 g/L (20 ºC) |
Merck | 14,2151 |
BRN | 509273 |
Stability: | Stable. Combustible. Incompatible with strong oxidizing agents, reducing agents, strong bases, alkali metals. |
InChIKey | BFCFYVKQTRLZHA-UHFFFAOYSA-N |
CAS DataBase Reference |
88-73-3(CAS DataBase Reference) |
IARC | 2B (Vol. 65, 123) 2020 |
NIST Chemistry Reference | Benzene, 1-chloro-2-nitro-(88-73-3) |
EPA Substance Registry System | o-Chloronitrobenzene (88-73-3) |
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